Being a seasoned professional by his early teens, he found work at Christie in 1912.
He followed his stint at Christie by joining Keystone and getting bits parts, even working with Charlie Chaplin.
After Sennett, Charley went to Fox pictures to write and direct for their comedy unit.
In 1920, he was hired by the other top producer of comedies at the time, Hal Roach. Charley would spend the next sixteen years developing his craft.
At Hal Roach Studios he became a director, at first for Snub Pollard, then supervising the early Our Gang shorts.
In late 1923, Charley decided to resume his comedy career in front of the camera.
His first screen character was "Jimmy Jump" virtually indistinguishable from any other comedian.
1924 turned out to be the year Charley turned it all around. He was given a new and young director by the name of Leo McCarey, who would later go on to direct such classics as "Duck Soup" with the Marx Brothers, "The Awful Truth" with Cary Grant and the holiday favorites "Going my Way" along with "The Bells of St. Mary's".
Charley and Leo developed a great friendship which made making movies very easy and stress free.
Chase made the decision to be himself in front of the camera. Like Harold Lloyd, he would be a regular guy. Also, and importantly he decided the comedy would not be thrown in just for the sake of comedy. From now on, the gags would have to integrate with the story.
Chase relied on two constant themes for his short comedies. He would either be a single guy on the lookout for pretty girl or a married guy with an overbearing wife.
Historically, Chase hasn't had the acclaim as the other silent greats, but with the advent of home video his fan base has grown outside of the die hard silent film buffs.
Chase practically invented the "situation comedy" in his short films and continued producing comedy till a battle with heavy drinking was lost in 1940.